Impact of family support on chemotherapy adherence among breast cancer patients: A Cross-Sectional Study in Indonesia

  • Muhammad Farhan Syahrefi Medical Education Study Program, Faculty of Medicine, Universitas Malahayati, Lampung, Indonesia
  • Upik Pebriyani Medical Education Study Program, Faculty of Medicine, Universitas Malahayati, Lampung, Indonesia
  • Muhammad Hatta Medical Education Study Program, Faculty of Medicine, Universitas Malahayati, Lampung, Indonesia
  • Asri Mutiara Putri Medical Education Study Program, Faculty of Medicine, Universitas Malahayati, Lampung, Indonesia
Keywords: Adherence, Breast Cancer, Chemotherapy, Family Support, Psychosocial

Abstract

Introduction: Breast cancer remains the most prevalent malignancy among Indonesian women, comprising approximately 30% of all cases. Most patients present in advanced stages, necessitating chemotherapy, which often causes side effects such as alopecia, nausea, and anxiety that may reduce treatment adherence. Family support plays a vital psychosocial role in enhancing motivation and compliance.

Methods: This observational analytical study employed a cross-sectional design at Dr. H. Abdul Moeloek Regional General Hospital, Bandar Lampung, from June 20–30, 2025. A total of 47 breast cancer patients undergoing chemotherapy were selected through purposive sampling. Family support was assessed via a validated questionnaire, and adherence data were extracted from medical records. The Chi-square test was applied with a significance level of α = 0.05.

Results: Most respondents were aged 46–60 (44.7%) and worked as housewives (55.3%). Good family support was reported by 68.1% of participants, and 72.3% demonstrated good chemotherapy adherence. Statistical analysis revealed a significant association between family support and chemotherapy adherence (p = 0.000 < 0.05). Patients with strong family support consistently showed higher adherence levels.

Conclusion: Family support significantly influences chemotherapy adherence in breast cancer patients. Interventions that strengthen family involvement could enhance treatment success and improve patient quality of life. Integrating psychosocial support into cancer care programs is essential to address both medical and emotional needs, thereby promoting optimal adherence and therapeutic outcomes

Downloads

Download data is not yet available.

References

Ahindu Konga, I. et al. (2025) ‘Direct and indirect costs of breast cancer management in Sub-Saharan Africa’, The Breast, 80, p. 104414. doi: https://doi.org/10.1016/j.jcpo.2025.100629.

Ben-Shlomo, S., Levin-Keini, N. and Meir, Y. (2025) ‘“Still in Transition”: Young adults’ retrospective accounts of foster care breakdown during adolescence’, Children and Youth Services Review, 177, p. 108478. doi: https://doi.org/10.1016/j.childyouth.2025.108478.

Dikeocha, I. J. et al. (2024) ‘Dietary interventions and tumor response to chemotherapy in breast cancer: A comprehensive review of preclinical and clinical data’, Clinical Nutrition ESPEN, 63, pp. 462–475. doi: https://doi.org/10.1016/j.clnesp.2024.06.048.

Ding, Y. et al. (2025) ‘Impact of social support on cognitive function in patients with breast cancer undergoing chemotherapy: The chain-mediating role of fatigue and depression’, Asia-Pacific Journal of Oncology Nursing, 12, p. 100743. doi: https://doi.org/10.1016/j.apjon.2025.100743.

Dona, A. C. et al. (2024) ‘Logistic burdens of cancer care: A qualitative study’, PLOS ONE. Edited by O. Ilozumba, 19(4), p. e0300852. doi: https://doi.org/10.1371/journal.pone.0300852.

Ford, K. et al. (2024) ‘Distal-Extremity Cryotherapy in Preventing Chemotherapy-Induced Peripheral Neuropathy from Paclitaxel Administration in People Affected by Breast Cancer: A Systematic Review’, Seminars in Oncology Nursing, 40(4), p. 151673. doi: https://doi.org/10.1016/j.soncn.2024.151673.

Geng, Z. et al. (2024) ‘Effectiveness of a theory-based tailored mHealth physical activity intervention for women undergoing chemotherapy for breast cancer: A quasi-experimental study’, International Journal of Nursing Sciences, 11(4), pp. 405–413. doi: https://doi.org/10.1016/j.ijnss.2024.08.006.

Guo, S. et al. (2025) ‘The chain mediating effects of psychological capital and illness perception on the association between social support and acceptance of illness among Chinese breast cancer patients: A cross-sectional study’, European Journal of Oncology Nursing, 75, p. 102800. doi: https://doi.org/10.1016/j.ejon.2025.102800.

Gyldenvang, H. H. et al. (2025) ‘Changing an exercise behaviour for physically inactive patients with breast cancer during chemotherapy- the critical role of nurse support: An implementation study’, European Journal of Oncology Nursing, 74, p. 102807. doi: https://doi.org/10.1016/j.ejon.2025.102807.

Haghmorad, D. et al. (2025) ‘Therapeutic challenges in breast cancer: Navigating the impact of oxidative stress on treatment efficacy and toxicity’, Biomedicine & Pharmacotherapy, 190, p. 118364. doi: https://doi.org/10.1016/j.biopha.2025.118364.

Lee, K. T. et al. (2025) ‘Hidden Costs of Endocrine Therapy for Black Breast Cancer Survivors: A Qualitative Examination of Patient and Provider Experiences’, Clinical Breast Cancer. doi: https://doi.org/10.1016/j.clbc.2025.06.010.

Li, H. et al. (2025) ‘The effect of symptom distress on medication adherence in patients with breast cancer undergoing endocrine therapy: A moderated mediation model’, Asia-Pacific Journal of Oncology Nursing, 12, p. 100701. doi: https://doi.org/10.1016/j.apjon.2025.100701.

Marmé, F. et al. (2024) ‘Palbociclib combined with endocrine treatment in hormone receptor-positive, HER2-negative breast cancer patients with high relapse risk after neoadjuvant chemotherapy: subgroup analyses of premenopausal patients in PENELOPE-B☆’, ESMO Open, 9(6), p. 103466. doi: https://doi.org/10.1016/j.esmoop.2024.103466.

Mason, S. R. E. et al. (2024) ‘Platinum chemotherapy for early triple-negative breast cancer’, The Breast, 75, p. 103712. doi: https://doi.org/10.1016/j.breast.2024.103712.

Mi, Y. et al. (2025) ‘Effects of Swanson theory-based auricular acupressure on chemotherapy-induced peripheral neuropathy, and broader health-related outcomes in patients with breast cancer: A randomized controlled trial’, Asia-Pacific Journal of Oncology Nursing, 12, p. 100729. doi: https://doi.org/10.1016/j.apjon.2025.100729.

Muthiyah A. AM, A. et al. (2023) ‘Self Efficacy of Self-Care Adherence in People with Hypertension’, Jurnal Ilmiah Kesehatan Sandi Husada, 12(1), pp. 216–223. doi: https://dx.doi.org/10.35816/jiskh.v12i1.1017.

Rast, M. et al. (2025) ‘Delays in chemotherapy and radiotherapy of breast cancer during COVID-19 pandemic’, Journal of Infection and Public Health, 18(3), p. 102657. doi: https://doi.org/10.1016/j.jiph.2025.102657.

Schladitz, K. et al. (2022) ‘Demands on Health Information and Clinical Practice Guidelines for Patients from the Perspective of Adults with Mental Illness and Family Members: A Qualitative Study with In-Depth Interviews’, International Journal of Environmental Research and Public Health, 19(21), p. 14262. doi: https://doi.org/10.3390/ijerph192114262.

Sharma, A., Sharma, N. and Chahal, A. (2024) ‘Impact of Virtual Reality on Pain, ROM, Muscle Strength and Quality of Life among Breast Cancer Patients: An Integrative Review of Literature’, Pain Management Nursing. doi: https://doi.org/10.1016/j.pmn.2024.04.015.

Valpey, R., Hale, E. and Kratzer, I. (2025) ‘Psychiatric Implications and Treatments for Patients Undergoing Treatment of Breast Cancer’, Advances in Psychiatry and Behavioral Health, 5(1), pp. 103–116. doi: https://doi.org/10.1016/j.ypsc.2025.02.011.

Wan, X. et al. (2024) ‘A study of the relationship and mediating effects of perceived stress and post-traumatic growth in patients undergoing postoperative chemotherapy for breast cancer’, European Journal of Oncology Nursing, 71, p. 102659. doi: https://doi.org/10.1016/j.ejon.2024.102659.

Wang, X. et al. (2025) ‘Effects of a multi-component positive psychological intervention on negative emotions, fatigue and quality of life in patients with breast cancer during initial chemotherapy: a randomized controlled trial’, European Journal of Oncology Nursing, 77, p. 102923. doi: https://doi.org/10.1016/j.ejon.2025.102923.

Xu, H., Li, H., Fan, Y., Wang, Y., et al. (2025) ‘Analysis of factors influencing chemotherapy-induced peripheral neuropathy in breast cancer patients using a random forest model’, The Breast, 81, p. 104457. doi: https://doi.org/10.1016/j.breast.2025.104457.

Xu, H., Li, H., Fan, Y., Zhang, S., et al. (2025) ‘Trajectory of Chemotherapy-Induced Peripheral Neuropathy and Its Predictive Factors in Breast Cancer Patients: A Prospective Longitudinal Study’, Clinical Breast Cancer. doi: https://doi.org/10.1016/j.clbc.2025.08.002.

Yu, X. et al. (2025) ‘Impact of social support on body image during chemotherapy in patients with breast cancer: The chain mediating role of depression and self-efficacy’, Asia-Pacific Journal of Oncology Nursing, 12, p. 100664. doi: https://doi.org/10.1016/j.apjon.2025.100664.

Yusriyanto, Y. and Asran, A. (2025) ‘Impact of PPE availability and safety training on occupational health implementation in rural construction projects: a cross-sectional study’, Jurnal Ilmiah Kesehatan Sandi Husada, 14(1), pp. 114–122. doi: https://doi.org/10.35816/jiskh.v14i1.1259.

Published
2025-12-12
How to Cite
Syahrefi, M., Pebriyani, U., Hatta, M. and Putri, A. (2025) “Impact of family support on chemotherapy adherence among breast cancer patients: A Cross-Sectional Study in Indonesia”, Jurnal Ilmiah Kesehatan Sandi Husada, 14(2), pp. 248-256. doi: 10.35816/jiskh.v14i2.1294.

Most read articles by the same author(s)

Obs.: This plugin requires at least one statistics/report plugin to be enabled. If your statistics plugins provide more than one metric then please also select a main metric on the admin's site settings page and/or on the journal manager's settings pages.