Analysis of risk factor microflora colonization on pregnancy vagina in makassar

  • Fardi Fardi Nursing Department, Mappa Oudang Nursing Academy, South Sulawesi, Indonesia
  • Rezeki Nur Nursing Department, Mappa Oudang Nursing Academy, South Sulawesi, Indonesia
  • Dewi Hestiani Nursing Department, Mappa Oudang Nursing Academy, South Sulawesi, Indonesia
Keywords: microflora colonization, prenatal care, pregnancy

Abstract

Introduction: Worldwide infection rates based on estimated 20-30 % colonization at 35 weeks gestation. During normal pregnancy colonization transient, intermittent, or chronic infection and the spectrum varies from asymptomatic colonization to the sepsis. Intrapartum transmission of bacteria from mother to neonatal, will cause the infection develops into neonatal sepsis during childbirth. This study aimed to determine the proportion of the colonization of gram positive and negative bacteria in pregnant women over 31 weeks of age.

Research Methodology: This research uses vaginal swab samples from pregnant women and blood samples from babies who are born, then these samples will be examined in the Unhas Hospital laboratory. Vaginal swab samples via transport medium will be placed in BHIB medium then incubated at 270 C for 24 hours.

Result: Prevalence of gram-positive bacterium identified Streptococcus species (0.9%), S. Aureus (11.8%) and S. Epidermidis (78.4%). For gram-negative bacteria had identified; Enterobacter Sp (32.3%), Providencia Sp (12.7%), Proteus Sp (8.8%), Acinetobacter sp (5.9%) and E. Coli (6.9%). Candida Sp obtained on SDA culture and gram staining followed by a number of 54 samples (55.1%). The symptom was to be is Discharge Vagina over 30% cases. Among 76.6% with habitually antiseptic usual. Based on data statistical analysis can be concluded that the age have a significance level 0:01 (ρ < 0.05) .and contraceptive used have a significance level of 0.038 (ρ < 0.05), had a relationship with a potential fetomaternal infection to infant.

Conclusion: that maternal age and history of contraceptive use are significantly associated with bacterial colonization in pregnant women. These findings underscore the need to consider demographic and behavioral factors when assessing and managing vaginal health during pregnancy. Effective educational interventions focusing on proper hygiene practices and the risks associated with antiseptic soap use, coupled with targeted monitoring of older pregnant women and those with a history of contraceptive use, are recommended to reduce the risks associated with vaginal microbial colonization

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References

Abavisani, M. et al. (2024) ‘The role of probiotics as adjunct treatment in the prevention and management of gynecological infections: An updated meta-analysis of 35 RCT studies’, Taiwanese Journal of Obstetrics and Gynecology, 63(3), pp. 357–368. Available at: https://doi.org/https://doi.org/10.1016/j.tjog.2024.03.004.

Arnianti, A., Adeliana, A. and Hasnitang, H. (2022) ‘Analysis of Risk Factors for Anemia in Pregnancy during the Covid-19 Pandemic’, Jurnal Ilmiah Kesehatan Sandi Husada, 11(2 SE-Articles). Available at: https://doi.org/https://doi.org/10.35816/jiskh.v11i2.807.

Baker, S. et al. (2023) ‘Efficacy of breast milk components against microbial pathogens to combat drug-resistance’, The Microbe, 1, p. 100010. Available at: https://doi.org/https://doi.org/10.1016/j.microb.2023.100010.

Bhatia, Z., Kumar, S. and Seshadri, S. (2024) ‘Composition and interaction of maternal microbiota with immune mediators during pregnancy and their outcome: A narrative review’, Life Sciences, 340, p. 122440. Available at: https://doi.org/https://doi.org/10.1016/j.lfs.2024.122440.

Buffington, P. et al. (2023) ‘Consequences of a cesarean section on the neonatal gut microbiome and future outcomes: a qualitative analysis of the literature’, Microbiota and Host, 1(1). Available at: https://doi.org/https://doi.org/10.1530/MAH-23-0006.

Chen, R. et al. (2024) ‘Effects of vaginal microbiota on human papillomavirus infection and its related diseases’, Microbial Pathogenesis, 193, p. 106761. Available at: https://doi.org/https://doi.org/10.1016/j.micpath.2024.106761.

Çömlekcioğlu, U. et al. (2024) ‘Uterine microbial ecology and disease in cattle: A review’, Theriogenology, 213, pp. 66–78. Available at: https://doi.org/https://doi.org/10.1016/j.theriogenology.2023.09.016.

Gorczyca, K. et al. (2024) ‘Premature rupture of membranes and changes in the vaginal microbiome – Probiotics’, Reproductive Biology, 24(3), p. 100899. Available at: https://doi.org/https://doi.org/10.1016/j.repbio.2024.100899.

Huang, Y. et al. (2024) ‘Nontoxigenic Bacteroides fragilis: A double-edged sword’, Microbiological Research, 286, p. 127796. Available at: https://doi.org/https://doi.org/10.1016/j.micres.2024.127796.

Jin, C. et al. (2023) ‘Comparative analysis of the vaginal microbiome of healthy and polycystic ovary syndrome women: a large cross-sectional study’, Reproductive BioMedicine Online, 46(6), pp. 1005–1016. Available at: https://doi.org/https://doi.org/10.1016/j.rbmo.2023.02.002.

Lan, J. and Chen, C. (2023) ‘The role of lactic acid bacteria in maintaining vaginal internal environment homeostasis in patients with infertility’, Microbial Pathogenesis, 176, p. 106004. Available at: https://doi.org/https://doi.org/10.1016/j.micpath.2023.106004.

Li, M. et al. (2024) ‘Relationship between infant gastrointestinal microorganisms and maternal microbiome within 6 months of delivery’, Microbiology Spectrum, 12(10). Available at: https://doi.org/https://doi.org/10.1128/spectrum.03608-23.

Mady, E.A. et al. (2023) ‘Impact of the mother’s gut microbiota on infant microbiome and brain development’, Neuroscience & Biobehavioral Reviews, 150, p. 105195. Available at: https://doi.org/https://doi.org/10.1016/j.neubiorev.2023.105195.

Mirzaei, R. et al. (2023) ‘Microbiota metabolites in the female reproductive system: Focused on the short-chain fatty acids’, Heliyon, 9(3), p. e14562. Available at: https://doi.org/https://doi.org/10.1016/j.heliyon.2023.e14562.

Molina, N.M. et al. (2024) ‘The complementary seminovaginal microbiome in health and disease’, Reproductive BioMedicine Online, p. 104707. Available at: https://doi.org/https://doi.org/10.1016/j.rbmo.2024.104707.

Mondal, A.S., Sharma, R. and Trivedi, N. (2023) ‘Bacterial vaginosis: A state of microbial dysbiosis’, Medicine in Microecology, 16, p. 100082. Available at: https://doi.org/https://doi.org/10.1016/j.medmic.2023.100082.

Nami, Y. et al. (2023) ‘A critical review of the recent concept of artificial mechanical uterus design in relation to the maternal microbiome: An Update to past researches’, Journal of Reproductive Immunology, 156, p. 103828. Available at: https://doi.org/https://doi.org/10.1016/j.jri.2023.103828.

Obuobi, S. and Škalko-Basnet, N. (2024) ‘Understanding vaginal biofilms: The first step in harnessing antimicrobial nanomedicine’, Journal of Controlled Release, 376, pp. 1190–1208. Available at: https://doi.org/https://doi.org/10.1016/j.jconrel.2024.10.064.

Roy, M., Majumdar, T. and Ray, J. (2024) ‘Vulvovaginal candidiasis in pregnant women attending a tertiary care centre in North-Eastern India’, Indian Journal of Medical Microbiology, 52, p. 100738. Available at: https://doi.org/https://doi.org/10.1016/j.ijmmb.2024.100738.

Turnip, M.S. and Kamso, S. (2024) ‘Pregnancy Examination with Postpartum Hemorrhage: SDKI Data Analysis 2017’, Jurnal Ilmiah Kesehatan Sandi Husada, 13(1), pp. 147–174. Available at: https://doi.org/https://doi.org/10.35816/jiskh.v13i1.1191.

Wei, X. et al. (2024) ‘Vaginal microbiomes show ethnic evolutionary dynamics and positive selection of Lactobacillus adhesins driven by a long-term niche-specific process’, Cell Reports, 43(4), p. 114078. Available at: https://doi.org/https://doi.org/10.1016/j.celrep.2024.114078.

Weng, T.-H. et al. (2023) ‘Microbiome analysis of maternal and neonatal microbial communities associated with the different delivery modes based on 16S rRNA gene amplicon sequencing’, Taiwanese Journal of Obstetrics and Gynecology, 62(5), pp. 687–696. Available at: https://doi.org/https://doi.org/10.1016/j.tjog.2023.07.033.

Wu, L.-Y. et al. (2024) ‘The role of probiotics in women’s health: An update narrative review’, Taiwanese Journal of Obstetrics and Gynecology, 63(1), pp. 29–36. Available at: https://doi.org/https://doi.org/10.1016/j.tjog.2023.09.018.

Published
2024-12-01
How to Cite
Fardi, F., Nur, R. and Hestiani, D. (2024) “Analysis of risk factor microflora colonization on pregnancy vagina in makassar”, Jurnal Ilmiah Kesehatan Sandi Husada, 13(2), pp. 366-372. doi: 10.35816/jiskh.v13i2.1225.

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